主要從事腦功能損傷與修復(fù)機(jī)制等相關(guān)的教學(xué)科研工作。近年來,以第一或通訊作者在Advanced Science、Archives of toxicology等知名期刊上發(fā)表高水平學(xué)術(shù)論文;研究成果被國際知名學(xué)者和領(lǐng)域綜述文獻(xiàn)多次正面引用評(píng)述,同時(shí)研究成果受到科技日?qǐng)?bào)、中國科學(xué)報(bào)、科學(xué)網(wǎng)、新華網(wǎng)等媒體專題報(bào)道。主持國家自然科學(xué)基金面上項(xiàng)目、青年基金,安徽省自然科學(xué)基金面上項(xiàng)目等多項(xiàng)縱向項(xiàng)目。目前實(shí)驗(yàn)室已經(jīng)成功搭建基于神經(jīng)網(wǎng)絡(luò)算法評(píng)估小鼠行為特征的算法模型,在體自由運(yùn)動(dòng)小鼠電生理采集及分析平臺(tái),光/化學(xué)控神經(jīng)環(huán)路平臺(tái)等,旨在逐步從多學(xué)科交叉角度系統(tǒng)揭示風(fēng)險(xiǎn)物暴露致大腦功能紊亂的生理機(jī)制以及潛在的功能小分子的修復(fù)機(jī)制。
歡迎對(duì)神經(jīng)生物學(xué)、機(jī)器學(xué)習(xí)、食品安全、功能小分子藥物等方向感興趣的同學(xué)加入。
學(xué)習(xí)經(jīng)歷:
2009年01月---2011年12月 香港中文大學(xué) 醫(yī)學(xué)院博士
2005年09月---2008年06月 中國科技大學(xué) 生命科學(xué)學(xué)院碩士
2000年09月---2004年06月 中南民族大學(xué) 生命科學(xué)學(xué)院學(xué)士
工作經(jīng)歷:
2022年12月---至今 合肥工業(yè)大學(xué)食品與生物工程學(xué)院 教授
2015年01月---2022.11合肥工業(yè)大學(xué)食品與生物工程學(xué)院 副教授
2012年07月---2014年12月 合肥工業(yè)大學(xué)食品與生物工程學(xué)院 副研究員
2012年01月---2012年06月 香港中文大學(xué) 醫(yī)學(xué)院Research Associate
1. Wentai Zhang; Linke Zhang; Weifeng Liang; Huan Wang; Fan Hu*; Neurodevelopment effects of early life bisphenol-A exposure on visual memory: Insights into recovery dynamics, Toxicology, 2024, 502: 153718. (IF= 4.571,?二區(qū))
2. Fan Hu*, Weifeng Liang, et al., Hyperactivity of basolateral amygdala mediates behavioral deficits in mice following exposure to bisphenol A and its analogue alternative.?Chemosphere. 2022. 287,?132044.?(IF= 8.943,?一區(qū),?top)
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3. Fan Hu*, Guangwei?Xu,?Linke?Zhang, Huan?Wang, Jiachen?Liu, Zhi?Chen, Yifeng?Zhou. Chronic bisphenol A?exposure triggers visual perception dysfunction through?impoverished neuronal coding ability in?the?primary visual cortex. Archives of toxicology.?2022 Feb;96(2):625-637. (IF= 6.168,?一區(qū), top)
4. Fan Hu*,?Linke Zhang, Tingting Li, Huan Wang, Weifeng Liang and Yifeng Zhou*. Bisphenol-A Exposure during Gestation and Lactation Causes Visual Perception Deficits in Rat Pups Following a Decrease in Interleukin 1b Expression in the Primary Visual Cortex. Neuroscience. 2020. 434, 148-160.?(IF=3.708)
5. Fan Hu*,?Jiachen Liu, Guangwei Xu, Huan Wang, Jiawei Shen, Yifeng Zhou* Bisphenol A exposure inhibits contrast sensitivity in cats involving increased response noise and inhibitory synaptic transmission.?Brain Research Bulletin. 2020. 157. 1-9.?(IF= 3.715)
6. Guangwei Xu1, Fan Hu1*,Xuan Wang, Bing Zhang, Yifeng Zhou*?Bisphenol A remodels visual response properties: decreased orientation selectivity and information fidelity.?Archives of toxicology. 2018.01.21,?92(1), 455-468.?(IF= 6.168,?一區(qū), top,co-first author and corresponding author)
7. Zhi Chen, Tingting Li, Linke Zhang, Huan Wang, Fan Hu* Bisphenol A exposure remodels cognition of male rats attributable to excitatory alterations in the hippocampus and visual cortex Toxicology. 2018. 410:132-141 (IF= 4.571,?二區(qū))
8. Fan Hu*,?Zhi Chen, Huarui Gong, Yan Jin, Tingting Li & Ming Wang*?Bisphenol A Impairs Synaptic Plasticity by both Pre- and Post-synaptic Mechanisms.?Advanced Science. 2017-4-10, DOI: 10.1002/advs.201600493?(IF= 17.521,?一區(qū), top)
9. Fan Hu1*, et al. The activity-regulated cytoskeletal-associated protein (Arc/Arg3.1) Involved in Developmental Lead Exposure Induced Dendrite and Spine Impairment in Rats.?Synapse. 2016. 70:87–97
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10. Mengmeng Ge1,F(xiàn)an Hu1, et al. Role of Wnt/b-catenin signaling in the protective effect of epigallocatechin-3-gallate on leadinduced impairments of spine formation in the hippocampus of rats.?RSC Advances. 2015, 5, 31622?(IF=3.361, co-first author)
11. Fan Hu, et al. Developmental lead exposure alters synaptogenesis through inhibiting canonical Wnt pathway in vivo and in vitro.?Plos one. 2014.06. 9(7), e101894
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12. Fan Hu, Chi Man Koon, Judy Yuet Wa Chan, Kit Man Lau, W.Y. Kwan, Kwok Pui Fung*. Involvements of calcium channel and potassium channel in Danshen and Gegen decoction induced vasodilation in porcine coronary LAD artery.?Phytomedicine. 2012; 19(12):1051-8.(IF= 6.656 ,?一區(qū),top)
13. Fan Hu, Judy YW Chan, Chi-Man Koon and Kwok-Pui Fung*. Angiogenic effects of Danshen and Gegen decoction In vivo and In vitro.?American Journal of Chinese Medicine. 2013; 41(4): 1–14 ?(IF=6.005, 二區(qū))
14. Fan Hu, Chi-Man Koon, Judy YW Chan, Kit-Man Lau and Kwok-Pui Fung*. Cardiac protection of the Danshen and gegen formula decoction in hypoxia/ischemia and reperfusion induced injury.?BMC Complement Altern Med. 2012; 12(1): 249.?(IF=4.782, 二區(qū))