碩士生導(dǎo)師

1、細胞自噬為核心的醫(yī)藥用納米材料的生物學(xué)效應(yīng)研究
2、納米細胞毒理學(xué)
3、基于生物學(xué)效應(yīng)研究的醫(yī)藥用納米材料改進策略

1、合肥工業(yè)大學(xué)人才引進科研啟動資金
2、國家自然科學(xué)基金 青年項目：幾種無機醫(yī)藥納米材料對自噬性溶酶體再生的影響研究 （編號31600813）（2017-2019）項目負責(zé)人
3、國家重大科學(xué)研究計劃：納米材料調(diào)控自噬的機制、安全性及在腫瘤診療中的應(yīng)用研究（編號2013CB933900）（2013-2017）學(xué)術(shù)骨干

代表性論文

[1] J.-Q. Zhang#, W. Zhou#*, S.-S. Zhu, J. Lin, P.-F. Wei, F.-F. Li, P.-P. Jin, H. Yao, Y.-J. Zhang, Y. Hu, Y.-M. Liu, M. Chen, Z.-Q. Li, X. Liu, L. Bai, L. Wen*. Persistency of Enlarged Autolysosomes Underscores Nanoparticle-Induced Autophagy in Hepatocytes. Small 2016, DOI 10.1002/smll.201602876.

[2] J. Zhang, W. Zhou*, J. Lin, P. Wei, Y. Zhang, P. Jin, M. Chen, N. Man, L. Wen*. Autophagic lysosomal reformation depends on mTOR reactivation in H2O2-induced autophagy. The International Journal of Biochemistry & Cell Biology 2016, 70, 76.

[3] J. Lin, S. Shi, J. Zhang, Y. Zhang, L. Zhang, Y. Liu, P. Jin, P. Wei, R. Shi, W. Zhou*, L. Wen*. Giant Cellular Vacuoles Induced by Rare Earth Oxide Nanoparticles are Abnormally Enlarged Endo/Lysosomes and Promote mTOR-Dependent TFEB Nucleus Translocation. Small 2016, 12, 5759.

[4] P. Jin, F. Li, R. Ruan, L. Zhang, N. Man, Y. Hu, W. Zhou*, L. Wen*. Enhanced Transdermal Delivery of Epidermal Growth Factor Facilitated by Dual Peptide Chaperone Motifs. Protein and Peptide Letters 2014, 21, 550.

[5] W. Zhou#, Y. Miao, Y. Zhang, L. Liu, J. Lin, J. Y. Yang, Y. Xie, L. Wen*. Induction of cyto-protective autophagy by paramontroseite VO2 nanocrystals. Nanotechnology 2013, 24, 165102.

[6] Ma, Yan ; Chen, Huajian; Hao Baimei; Zhou Junhong; He Gang; Miao Zhaohua *; Xu Yan; Gao Li; Zhou Wei*; Zha Zhengbao*, A chloroquine-loaded Prussian blue platform with controllable autophagy inhibition for enhanced photothermal therapy, Journal of Materials Chemistry B, 2018.10.7, 6(37)：5854~5859.

[7] Benjin Chen, Yifei Jiang, Mengli Zhao, Wanni Wang, Zhaoyou Chu, Ronghua Huo, Fan Hu, Wei Zhou*, Tao He*, Haisheng Qian*, Ag nanoparticles decorated hybrid microspheres for superior antibacterial properties,Materials Letters,Volume 262,2020,127057

[8] Hao BM, Liu YN, Zhang CY, Li GQ, Wang WN, Xu WD, Zha ZB, Wang F, Li C, Miao ZH, Yang XX, Chen YL, Qian HS, Zhou W. Autophagic blockage by bismuth sulfide nanoparticles inhibits migration and invasion of HepG2 cells. Nanotechnology. 2020 Nov 13;31(46):465102.