以通訊作者共發(fā)表研究論文60余篇,包括Nature Chem. Biol.、Nature Commun.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、JACS Au、CCS Chem.等,
近年來主要代表作如下:
1.Wang, Y.; Fan, J.; Meng, X.; Shu, Q.; Wu, Y.; Chu, G.; Ji, R., Ye, Y. S.; Wu, X. W.; Shi, J.; Deng, H.; Liu, L.*; Li, Y.-M.* Development of nucleus-targeted histone-tail-based photoaffinity probes to profile the epigenetic interactome in native cells. Nature Commun. 2025, 16, 415.
2.Wang, Y.; Liu, L.; Zheng, Q.Y.; Wu, Y.; Su, Z.; Yuan, R.J.; Xia, Q.; Wang, B.; Yu, Y.;* Li, Y.-M.* Synergizing Structure-Guided Photocaged Linear Diubiquitin-Dha with Biotinylated Linear-Fab for Time-Resolved Profiling of Interactors in Living Cells. J. Am. Chem. Soc. 2025, doi.org/10.1021/jacs.5c15159.
3.Zhao R., Shi P., Cui J. B., Shi C. W., Wei X. X., Luo J., Xia Z. M., Shi W. W., Zhou Y. X., Tang J. H., Tian C. L., Meininghaus M., Bierer D., Shi J.*, Li Y.-M.*, Liu L.*, Single-Shot Solid-Phase Synthesis of Full-Length H2 Relaxin Disulfide Surrogates. Angew. Chem. Int. Ed. 2023, 62, e202216365.
4.Chu, G. C.; Li, Y.-M.* Lighting up kinase contacts in situ. Nature Chem. Biol. 2024, 20, 544.
5.Wang, Y.; Chen, J. N.; Hua, X.; Meng, X. B.; Cai, H. Y.; Wang, R. T.; Shi, J.; Deng, H. T.; Liu, L.; Li, Y.-M.* Photocaging of Cell-permeable Activity-based Ubiquitin Probes via a C-Terminal Backbone Modification Strategy. Angew. Chem. Int. Ed. 2022, 61, e202203792.
6.Zheng, Q. Y.; Wang, T.; Chu, G. C.; Zuo, C.; Zhao, R.; Sui X.; Ye, L.; Yu, Y., Chen, J Zhang, W.; Deng, H.; Shi, J.; Pan, M.*; Li, Y.-M.*; Liu, L.* An E1-Catalyzed Chemoenzymatic Strategy to Isopeptide-N-Ethylated Deubiquitylase-Resistant Ubiquitin Probes, Angew. Chem. Int. Ed. 2020, 59, 13496.
7.Wang, Y.; Chen, C. C.; Meng, X.; Fan, J.; Pan, M.; Chen, J; Deng, H.; Shi, J.*; Liu, L.; Li, Y.-M.* Chemical Synthesis of diSUMO Photoaffinity Probes for the Identification of PolySUMO-Chain Specific Interacting Proteins. CCS Chem. 2020, 3, 1157.
8.Chu, G. C.; Pan, M.; Li, J.; Liu, S.; Zuo, C.; Tong, Z.-B.; Bai, J.-S.; Gong, Q.; Ai, H.; Fan, J.; Meng, X.; Huang, Y.; Shi, J.; Deng, H.; Tian, C.*; Li, Y.-M.*; Liu, L.* Cysteine-Aminoethylation Assisted Chemical Ubiquitination of Recombinant Histones, J. Am. Chem. Soc. 2019, 141, 3654.
9.Li, Y. T.; Yi, C.; Chen, C. C.; Lan, H.; Pan, M.; Zhang, S. J.; Huang, Y. C.; Guan, C. J.; Li, Y.-M.*; Yu, L.*; Liu, L.* A semisynthetic Atg3 reveals that acetylation promotes Atg3 membrane binding and Atg8 lipidation. Nature Commun. 2017, 8, 14846.
專利
1. 鏈間二硫鍵CysA24-CysB23替代為硫醚鍵的H2 Relaxin衍生物,專利授權(quán)號(hào):2022 1 1323902.X
2.一種口腔鱗狀細(xì)胞癌診斷生物標(biāo)志物hsa-miR-331-3p及其應(yīng)用,專利授權(quán)號(hào):2024 1 1441126.2
3.一種新型環(huán)狀聚精氨酸穿膜肽分子及其合成方法和應(yīng)用,專利授權(quán)號(hào):202110526684.9
4.一種簡(jiǎn)易合成泛素探針Ub-Rho110-Gly的方法,專利授權(quán)號(hào):201910179861.3
5.一種用于二泛素合成的新型輔基連接臂及其合成方法和應(yīng)用,專利授權(quán)號(hào):201910025364.8
6.一種環(huán)保型正交保護(hù)的二氨基二酸類化合物、其制備方法及其應(yīng)用,專利授權(quán)號(hào):201710498209.9
著作
《化學(xué)生物學(xué)實(shí)驗(yàn)》,中國(guó)科學(xué)技術(shù)大學(xué)出版社 編委