副教授

1.食品微生物合成生物學
2.食品酶在微生物中的發(fā)酵生產(chǎn)
3.活性功能物質(zhì)在微生物中的分泌機制
4.食品酶的功能與結(jié)構(gòu)研究
5.食品酶在食品加工過程中的應(yīng)用
6.微生物抗菌多肽的生物合成與修飾
開設(shè)課程
專業(yè)課：《食品酶學》、《食品衛(wèi)生學》、《生物工程專業(yè)英語》、《生物技術(shù)專業(yè)英語》
公選課：《遺傳學發(fā)現(xiàn)》、《生物安全》

1.國家自然科學基金面上項目（32472299），2025.01-2028.12，項目負責人。
2.國家重點研發(fā)計劃項目子課題（2025YFF1107300），子課題負責人。
3.中國博士后科學基金（2019M651013），2019.07-2022.06，項目負責人。
4.安徽省科技重大專項（201903a06020007），2019.09-2022.08，項目負責人。
5.安徽省自然科學基金面上項目（2408085MC082），2025.01-2027.12，項目負責人。
6.安徽省自然科學基金面上項目（2108085MC123），2021.01-2023.12，項目負責人。
7.安徽省自然科學基金青年項目（1708085QC65），2017.01-2019.12，項目負責人。
8.橫向項目（W2024JSFW0924），2024.10-2027.10，項目負責人。
9.橫向項目（W2023JSKF0788），2023.11-2025.10，項目負責人。
10.橫向項目（W2022JSFW0296），2022.01-2024.12，項目負責人。
11.橫向項目（W2021JSKF1070），2021.01-2023.12，項目負責人。
12.橫向項目（W2020JSKF0538），2020.01-2023.12，項目負責人。
13.中央高校博士專項科研資助基金（JZ2016HGBZ0777），2017.01-2018.12，項目負責人。
14.中央高校博士專項科研資助基金（PA2021KCPY0048），2021.01-2022.12，項目負責人。
15.安徽省重點實驗室自主創(chuàng)新專項（PA2019GDPK0063），2019.01-2020.12，項目負責人。
16.茶樹生物學與資源利用國家重點實驗室開放基金（SKLTOF20180107），2018.01-2019.12，項目負責人。

一、代表性論文（*通訊作者；#共同一作）
2025
24. Mu D*, Wang D*, Montalbán-López M, Wu X, Li X*. Enhancement of Thermostability and Catalytic Activity of β-1,4-Xylanase via Rational and Semi-rational Collaborative Engineering. Journal of Agricultural and Food Chemistry. 2025, 73(45):28946-28964.
23. Zhang X, Montalbán-López M, Li X, Wu X, Mu D*. Metabolic Engineering of Lactococcus lactis for the Enhanced Production of Lactate by Manipulating Pyruvate Dehydrogenase Complex E2 and Lactate Dehydrogenase. Journal of Agricultural and Food Chemistry. 2025, 73(40):25549-25561.
22. Ai Y, Montalbán-López M, Li P, Zhang H, Wu X, Li X*, Mu D*. Semirational Design and Immobilization Synergistically Enhance Barnase Activity and Stability. Journal of Agricultural and Food Chemistry. 2025, 73(16):9743-9758.
2024
21. Ma T, Li X, Montalbán-López M, Wu X, Zheng Z*, Mu D*. Effect of the Membrane Insertase YidC on the Capacity of Lactococcus lactis to Secret Recombinant Proteins. Journal of Agricultural and Food Chemistry. 2024, 72, 23320?23332.
20. Wei D, Ma T, Montalbán-López M, Li X, Wu X, Mu D*. Enhanced Production, Enzymatic Activity, and Thermostability of an α-Amylase from Bacillus amyloliquefaciens in Lactococcus lactis. Journal of Agricultural and Food Chemistry. 2024, 72, 24587?24598.
19. Ai Y#, Kang N#, Montalbán-López M, Wu X, Li X*, Mu D*. Enhanced stability, quality and flavor of bread through sourdough fermentation with nisin-secreting Lactococcus lactis NZ9700. Food Bioscience. 62 (2024) 105484.
18. Mu D#*, Li P#, Ma T#, Wei D#, Montalbán-López M, Ai Y, Wu X, Wang Y, Li X, Li X*. Advances in the understanding of the production, modification and applications of xylanases in the food industry. Enzyme and Microbial Technology. 2024 Sep:179:110473.
2023
17. Ai Y, Li X, Wu X, Montalbán-López M, Zheng Z, Mu D*. Secreting recombinant barnase by Lactococcus lactis and its application in reducing RNA from forages. Enzyme and Microbial Technology. 2023 Mar;164:110191.
2022
16. Ma T, Li X, Montalbán-López M, Wu X, Zheng Z*, Mu D*. Secretion of Bacillus amyloliquefaciens Transglutaminase from Lactococcus lactis and Its Enhancement of Food Gel Properties. Gels. 2022, 8, 674.
15. Bao S, Li X, Wu X, Montalbán-López M, Qiao M, Zheng Z, Cai J, and Mu D*. Secretion of Bacillus amyloliquefaciens Levansucrase and Its Mutants from L. lactis NZ9000 and Their Applications in the Synthesis of Levan. ACS Food Science & Technology. 2022, 2, 4, 655-666.
2021
14. Ma T, Li X, Wu X, Jiang S, Zheng Z* and Mu D*. Expression of Bacillus amyloliquefaciens γ-glutamyltransferase in Lactococcus lactis and immobilization on magnetic nanoparticles. ACS Food Science & Technology. 2021, 1, 5, 778-787.
13. Mu D*, Zhou Y, Wu X, Montalban-Lopez M, Wang L, Li X, and Zheng Z. Secretion of Bacillus amyloliquefaciens Levansucrase from Bacillus subtilis and Its Application in the Enzymatic Synthesis of Levan. ACS Food Science & Technology. 2021, 1, 2, 249-259.
2020
12. Mu D, Li H, Li X, Zhu J, Qiao M, Wu X, Luo S, Yang P, Zhao Y, Liu F, Jiang S, Zheng Z*. Enhancing laccase-induced soybean protein isolates gel properties by microwave pretreatment, Journal of Food Processing and Preservation. 2020, 44(4): e14386.
2019
11. Mu D*#, Li H#, Chen Q#, Zhu J, Wu X, Luo S, Zhao Y, Wang L, Jiang S, Li X*, Zheng Z*. Secretion of Bacillus amyloliquefaciens γ-Glutamyltranspeptidase from Bacillus subtilis and its application in enzymatic synthesis of l-theanine, Journal of Agricultural and Food Chemistry. 2019, 67(51):14129-14136.
10. Ma T#, Lu J#, Zhu J#, Li X, Gu H, Montalbán-López M, Wu X, Luo S, Zhao Y, Jiang S, Zheng Z*, Mu D*. The secretion of Streptomyces monbaraensis transglutaminase from Lactococcus lactis and immobilization on porous magnetic nanoparticles, Frontiers in Microbiology. 2019, 10:1675.
2018
9. Mu D*#, Lu J#, Qiao M, Kuipers OP, Zhu J, Li X, Yang P, Zhao Y, Luo S, Wu X, Jiang S, Zheng Z. Heterologous signal peptides-directing secretion of Streptomyces mobaraensis transglutaminase by Bacillus subtilis, Applied Microbiology and Biotechnology, 2018. 102(13):5533-5543.
8. Mu D, Lu J, Shu C, Li H, Li X, Cai J, Luo S, Yang P, Jiang S, Zheng Z. Improvement of the activity and thermostability of microbial transglutaminase by multiple-site mutagenesis, Bioscience Biotechnology & Biochemistry, 2018, 82:1, 106-109.
2017
7. Wang K, Li C, Wang B, Yang W, Luo S, Zhao Y, Jiang S, Mu D*, Zheng Z*. Formation of macromolecules in wheat gluten/starch mixtures during twin-screw extrusion: effect of different additives. Journal of the Science of Food and Agriculture. 2017 Dec; 97(15):5131-5138. doi: 10.1002/jsfa.8392.
2016
6. Alvarez-Sieiro P, Montalbán-López M, Mu D, Kuipers OP*, Bacteriocins of lactic acid bacteria: extending the family, Applied Microbiology and Biotechnology, 2016 100(7): 2939-2951.
2015
5. Mu D, Montalbán-López M, Deng J, Kuipers OP*, Lantibiotic reductase LtnJ substrate selectivity assessed with a collection of nisin derivatives as substrates, Applied and Environmental Microbiology, 2015, 81(11):3679-3687.
2013
4. Mu D, Montalbán-López M, Masuda Y, Kuipers OP*, Zirex: a novel zinc-regulated expression system for Lactococcus lactis, Applied and Environmental Microbiology, 2013, 79(14):4503-4508.
3. van Heel AJ#, Mu D#, Montalbán-López M, Hendriks D, Kuipers OP*, Designing and producing modified, new-to-nature peptides with antimicrobial activity by use of a combination of various lantibiotic modification enzymes, ACS Synthetic Biology, 2013, 2(7): 397-404.
2011
2. Yin Y, Mu D*, Chen S, Liu L, Wang Z*, Effects on growth and digestive enzyme activities of the Hepialus gonggaensis larvae caused by introducing probiotics, World Journal of Microbiology and Biotechnology, 2011, 27(3): 529-533.
2010
1. 穆冬冬，王中康，殷幼平，飼喂肉桿菌Hg4-03對貢嘎蝠蛾幼蟲腸菌生物多樣性的影響，微生物學報，2010，50 (02).
二、授權(quán)專利
1.一種β-1,4-木聚糖酶突變體及其構(gòu)建方法，專利號：ZL 202511095123.2

1.安徽省食品創(chuàng)新設(shè)計大賽一等獎（2020）、二等獎（2021）、三等獎（2018、2020）
2.安徽省食品創(chuàng)新設(shè)計大賽優(yōu)秀指導(dǎo)教師（2020）
3.安徽省科技進步一等獎（R9）（2025）
4.合肥工業(yè)大學畢業(yè)設(shè)計優(yōu)秀指導(dǎo)教師（2025）