食品生物技術(shù)系

1.園藝作物成熟衰老相關(guān)基因的功能研究
（1）以番茄等園藝作物為材料，利用轉(zhuǎn)基因技術(shù)、基因編輯技術(shù)，從分子水平解析成熟衰老相關(guān)基因的作用機(jī)制；
（2）解析硫化氫、乙烯等信號(hào)分子對(duì)果蔬采后衰老的調(diào)控作用。
2.果蔬采后儲(chǔ)藏過(guò)程中的衰老機(jī)制解析
（1）解析果蔬采后衰老的生物學(xué)基礎(chǔ)；
（2）解析硫化氫、乙烯等信號(hào)分子對(duì)果蔬采后衰老的調(diào)控作用。

1. 國(guó)家自然科學(xué)基金面上項(xiàng)目：半胱氨酸脫巰基酶LCD調(diào)控番茄果實(shí)成熟衰老的機(jī)制研究(項(xiàng)目號(hào)31970200)，2020.01-2023.12，主持人。
2. 安徽省科技攻關(guān)項(xiàng)目：大豆磷脂精深加工技術(shù)開(kāi)發(fā)及高值化功能磷脂產(chǎn)品的產(chǎn)業(yè)化應(yīng)用，2024.09-2026.12，主持人。
3. 合肥工業(yè)大學(xué)優(yōu)秀青年人才培育計(jì)劃A項(xiàng)目：植物中巰基化修飾蛋白的鑒定及功能研究(項(xiàng)目號(hào)JZ2021HGPA0063)，2021.05-2023.12，主持人。
4. 合肥工業(yè)大學(xué)應(yīng)用培育計(jì)劃項(xiàng)目：番茄病蟲(chóng)害防治及優(yōu)質(zhì)高產(chǎn)技術(shù)開(kāi)發(fā)(項(xiàng)目號(hào)JZ2020YYPY0249)，2020.06-2021.06，主持人。
5. 安徽元?jiǎng)?chuàng)科技有限公司橫向課題：大豆磷脂提取工藝及磷脂產(chǎn)品技術(shù)開(kāi)發(fā)(項(xiàng)目號(hào)W2020JSKF0843)，2020.12-2021.12，主持人。
6. 安慶市中創(chuàng)工程技術(shù)有限責(zé)任公司橫向課題：功能性磷脂合成的關(guān)鍵技術(shù)及其生理功能研究(項(xiàng)目號(hào)W2020JSFW0483)，2020.12-2021.12，主持人。
7. 江蘇徐淮地區(qū)徐州農(nóng)業(yè)科學(xué)研究所橫向課題：甘薯葉片抗衰老性與其耐貯性相關(guān)分析及快捷鑒定技術(shù)(項(xiàng)目號(hào)W2020JSKF0842)，2018.05-2019.12，主持人。
8. 中央高校基本科研業(yè)務(wù)費(fèi)學(xué)術(shù)新人B項(xiàng)目：半胱氨酸脫巰基酶LCD調(diào)控番茄果實(shí)成熟衰老的機(jī)制研究(項(xiàng)目號(hào)JZ2018HGTB0241)，2018.5-2019.12，主持人。
9. “國(guó)家甘薯產(chǎn)業(yè)技術(shù)體系建設(shè)”子課題：耐儲(chǔ)藏甘薯資源的篩選與鑒定(項(xiàng)目號(hào)CARS-11-B-02)，2011.01-2020.12，主持人。
10. 國(guó)家自然科學(xué)基金項(xiàng)目：蛋白磷酸酶去活化cAMP通路調(diào)控白色念珠菌形態(tài)轉(zhuǎn)變的機(jī)制研究(項(xiàng)目號(hào)31300133)，2014.01-2016.12，主持人。

代表性論文
1.Ying Sun, Min Zhang, Menghui Geng, Zhikun Geng, Zixu Lu, Nannan Liu,Zhanmin Liu, Dexin Zeng, Gaifang Yao, Kangdi Hu*(通訊作者), Hua Zhang*(通訊作者). Hydrogen sulfide interferes with ethylene biosynthesis and signaling pathway in tomato by the mediation of SlERF.D2 persulfidation. Plant Journal. 2025, 121(4) DOI: 10.1111/tpj.70000
2.Kangdi Hu?,*(通訊作者), Meihui Geng?, Lin Ma?, Gaifang Yao, Min Zhang, Hua Zhang*(通訊作者). H2S-responsive ERF.D3 regulates tomato leaf senescence and fruit ripening by modulating abscisic acid metabolism. Plant Physiology, 2025, 197(2)
3.Min Zhang, Kangdi Hu*(通訊作者), Lin Ma, Meihui Geng, Conghe Zhang, Gaifang Yao, and Hua Zhang*(通訊作者). Persulfidation and phosphorylation of transcription factor SlWRKY6 differentially regulate tomato fruit ripening. Plant Physiology, 2024, 196(1), 210–227. DOI:10.1093/plphys/kiae271
4. Yu-Qi Zhao#, Kang-Di Hu#*(通訊作者), Gai-Fang Yao, Si-Yue Wang, Xiang-Jun Peng, Hua Zhang*(通訊作者). A D-cysteine desulfhydrase, SlDCD2, participates in tomato fruit ripening by modulating ROS homoeostasis and ethylene biosynthesis. Horticulture Research. 2023, 10(3), uhad014.
5.Kangdi Hu#(通訊作者), Xiangjun Peng#, Gaifang Yao, Zhilin Zhou, Feng Yang, Wanjie Li, Yuqi Zhao, Yanhong Li, Zhuo Han, Xiaoyan Chen, Hua Zhang*(通訊作者). Roles of a cysteine desulfhydrase LCD1 in regulating leaf senescence in tomato. International Journal of Molecular Sciences. 2021, 22: 13078.
6.Li-Xia Li#, Zeng-Zheng Wei#, Zhi-Lin Zhou#, Dong-Lan Zhao, Jun Tang, Feng Yang, Yan-Hong Li, Xiao-Yan Chen, Zhuo Han, Gai-Fang Yao*(通訊作者), Kang-Di Hu*(通訊作者), Hua Zhang*(通訊作者). A single amino acid mutant in the EAR motif of IbMYB44.2 reduced the inhibition of anthocyanin accumulation in the purple-fleshed sweetpotato. Plant Physiology and Biochemistry. 2021, 167: 410-419.
7.Kang-Di Hu#, Xiao-Yue Zhang#, Gai-Fang Yao#, Yu-Lei Rong, Chen Ding, Jun Tang, Feng Yang, Zhong-Qin Huang, Zi-Mu Xu, Xiao-Yan Chen, Yn-Hong Li, Lan-Ying Hu, Hua Zhang*(通訊作者). A nuclear-localized cysteine desulfhydrase plays a role in fruit ripening in tomato. Horticulture Research. 2020, 7(1): 211.
8.Gai-Fang Yao#, Zeng-Zheng Wei#, Ting-Ting Li#, Jun Tang, Zhong-Qin Huang, Feng Yang, Yan-Hong Li, Zhuo Han, Fan Hu, Lan-Ying Hu, Kang-Di Hu*(通訊作者), Hua Zhang*(通訊作者). Modulation of enhanced antioxidant activity by hydrogen sulfide antagonizing ethylene in tomato fruit ripening. Journal of Agricultural and Food Chemistry. 2018, 66(40):10380-10387.
9.Shi-Ping Li#, Kang-Di Hu#, Lan-Ying Hu, Yan-Hong Li, An-Min Jiang, Fang Xiao, Yi Han, Yong-Sheng Liu, Hua Zhang*(通訊作者). Hydrogen sulfide alleviates postharvest senescence of broccoli by modulating antioxidant defense and senescence-related gene expression. Journal of Agricultural and Food Chemistry. 2014, 62(5): 1119-1129.
10.Kang-Di Hu#, Xiao-Yue Zhang#, Sha-Sha Wang, Jun Tang, Feng Yang, Zhong-Qin Huang, Jing-Yu Deng, Si-Yuan Liu, Shang-Jun Zhao, Lan-Ying Hu, Gai-Fang Yao*(通訊作者), Hua Zhang*(通訊作者). Hydrogen sulfide inhibits fruit softening by regulating ethylene synthesis and signaling pathway in tomato (Solanum lycopersicum). HortScience, 2019, 54 (10), 1824-1830.
11.Shang-Xuan Guo#, Gai-Fang Yao#, Hui-Ran Ye#, Jun Tang, Zhong-Qin Huang, Feng Yang, Yan-Hong Li, Zhuo Han, Lan-Ying Hu, Hua Zhang*(通訊作者), Kang-Di Hu*(通訊作者). Functional Characterization of a Cystathionine β-Synthase Gene in Sulfur Metabolism and Pathogenicity of Aspergillus niger in Pear Fruit. Journal of Agricultural and Food Chemistry. 2019, 67 (16): 4435-4443.
12.Gai-Fang Yao#, Zeng-Zheng Wei#, Ting-Ting Li#, Jun Tang, Zhong-Qin Huang, Feng Yang, Yan-Hong Li, Zhuo Han, Fan Hu, Lan-Ying Hu, Kang-Di Hu*(通訊作者), Hua Zhang*(通訊作者). Modulation of enhanced antioxidant activity by hydrogen sulfide antagonizing ethylene in tomato fruit ripening. Journal of Agricultural and Food Chemistry. 2018, 66(40):10380-10387.
13.Kang-Di Hu#, Gui-Sheng Bai, Wan-Jie Li, Hong Yan, Lan-Ying Hu, Yan-Hong Li, Hua Zhang*(通訊作者). Sulfur dioxide promotes germination and plays an antioxidant role in cadmium stressed wheat seeds. Plant Growth Regulation. 2015, 75 (1): 271-280.
專(zhuān)利
1.一種促進(jìn)花青苷合成的PyWRKY31基因及其重組表達(dá)載體與應(yīng)用，專(zhuān)利授權(quán)號(hào)：201911385943.X.
2.一種促進(jìn)番茄果實(shí)成熟的基因及其調(diào)控方法. 專(zhuān)利申請(qǐng)?zhí)枺?02210850569.1

1. 2019年度新疆維吾爾自治區(qū)科學(xué)技術(shù)獎(jiǎng)二等獎(jiǎng),甘薯優(yōu)良品種評(píng)價(jià)利用及配套栽培 技術(shù)集成應(yīng)用。
2. 擔(dān)任Plant Hormones青年編委，擔(dān)任Journal of Experimental Botany、Postharvest Biology and Technology 雜志審稿人。